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DMAP-assisted sulfonylation as an efficient step for the methylation of primary amine motifs on solid support
Several multistep strategies were developed to ensure single methylation of amines on solid support. These strategies rely on the introduction of the o-NBS protecting/activating group as a key step. We found that the state-of-the-art strategies fail for the methylation of several primary amine motif...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433225/ https://www.ncbi.nlm.nih.gov/pubmed/28546838 http://dx.doi.org/10.3762/bjoc.13.81 |