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The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaques) and of tau protein, which form neurofibrilla...

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Detalles Bibliográficos
Autores principales: Lackie, Rachel E., Maciejewski, Andrzej, Ostapchenko, Valeriy G., Marques-Lopes, Jose, Choy, Wing-Yiu, Duennwald, Martin L., Prado, Vania F., Prado, Marco A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433227/
https://www.ncbi.nlm.nih.gov/pubmed/28559789
http://dx.doi.org/10.3389/fnins.2017.00254