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Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

The vast majority of neurodegenerative pathologies stem from the formation of toxic oligomers and aggregates composed of wrongly folded proteins. These protein complexes can be released from pathogenic cells and enthralled by other cells, causing the formation of new aggregates in a prion-like manne...

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Detalles Bibliográficos
Autores principales: Lazarev, Vladimir F., Mikhaylova, Elena R., Guzhova, Irina V., Margulis, Boris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433261/
https://www.ncbi.nlm.nih.gov/pubmed/28559794
http://dx.doi.org/10.3389/fnins.2017.00277