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Preclinical safety & toxicity evaluation of pooled, allogeneic human bone marrow-derived mesenchymal stromal cells

BACKGROUND & OBJECTIVES: Administration of ex vivo-expanded human bone marrow-derived mesenchymal stromal cells (hBMMSC) obtained from single donors has shown therapeutic benefits in both preclinical and clinical studies. In this study, the safety, toxicity and biodistribution profiles of a pool...

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Detalles Bibliográficos
Autores principales: Rengasamy, Mathiyazhagan, Gupta, Pawan Kumar, Kolkundkar, Udaykumar, Singh, Gurbind, Balasubramanian, Sudha, SundarRaj, Swathi, Chullikana, Anoop, Majumdar, Anish Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433278/
https://www.ncbi.nlm.nih.gov/pubmed/28474622
http://dx.doi.org/10.4103/ijmr.IJMR_1842_15