Genetic polymorphisms of N-acetyltransferase 2 & susceptibility to antituberculosis drug-induced hepatotoxicity

BACKGROUND & OBJECTIVES: The N-acetyltransferase 2 (NAT2) gene encodes an enzyme which both activates and deactivates arylamine and other drugs and carcinogens. This study was aimed to investigate the role of NAT2 gene polymorphism in anti-tuberculosis drug-induced hepatotoxicity (DIH). METHODS:...

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Detalles Bibliográficos
Autores principales: Sharma, Surendra K., Jha, Brajesh Kumar, Sharma, Abhishek, Sreenivas, V., Upadhyay, Vishwanath, Jaisinghani, Chandrita, Singla, Rohit, Mishra, Hemant Kumar, Soneja, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433286/
https://www.ncbi.nlm.nih.gov/pubmed/28474630
http://dx.doi.org/10.4103/ijmr.IJMR_684_14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433286/
https://www.ncbi.nlm.nih.gov/pubmed/28474630
http://dx.doi.org/10.4103/ijmr.IJMR_684_14

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