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Altered Erythropoiesis in Mouse Models of Type 3 Hemochromatosis

Type 3 haemochromatosis (HFE3) is a rare genetic iron overload disease which ultimately lead to compromised organs functioning. HFE3 is caused by mutations in transferrin receptor 2 (TFR2) gene that codes for two main isoforms (Tfr2α and Tfr2β). Tfr2α is one of the hepatic regulators of iron inhibit...

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Detalles Bibliográficos
Autores principales: Pellegrino, R. M., Riondato, F., Ferbo, L., Boero, M., Palmieri, A., Osella, L., Pollicino, P., Miniscalco, B., Saglio, G., Roetto, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433419/
https://www.ncbi.nlm.nih.gov/pubmed/28540293
http://dx.doi.org/10.1155/2017/2408941