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Altered Erythropoiesis in Mouse Models of Type 3 Hemochromatosis
Type 3 haemochromatosis (HFE3) is a rare genetic iron overload disease which ultimately lead to compromised organs functioning. HFE3 is caused by mutations in transferrin receptor 2 (TFR2) gene that codes for two main isoforms (Tfr2α and Tfr2β). Tfr2α is one of the hepatic regulators of iron inhibit...
Autores principales: | Pellegrino, R. M., Riondato, F., Ferbo, L., Boero, M., Palmieri, A., Osella, L., Pollicino, P., Miniscalco, B., Saglio, G., Roetto, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433419/ https://www.ncbi.nlm.nih.gov/pubmed/28540293 http://dx.doi.org/10.1155/2017/2408941 |
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