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Site selective reading of epigenetic markers by a dual-mode synthetic receptor array

Variably functionalized self-folding deep cavitands form an arrayed, fluorescent indicator displacement assay system for the detection of post-translationally modified (PTM) histone peptides. The hosts bind trimethyllysine (KMe(3)) groups, and use secondary upper rim interactions to provide more sen...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Perez, Lizeth, Mettry, Magi, Gill, Adam D., Byers, Samantha R., Easley, Connor J., Bardeen, Christopher J., Zhong, Wenwan, Hooley, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433514/
https://www.ncbi.nlm.nih.gov/pubmed/28553538
http://dx.doi.org/10.1039/c7sc00865a