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Disease-associated mitochondrial mutations and the evolution of primate mitogenomes

Several human diseases have been associated with mutations in mitochondrial genes comprising a set of confirmed and reported mutations according to the MITOMAP database. An analysis of complete mitogenomes across 139 primate species showed that most confirmed disease-associated mutations occurred in...

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Detalles Bibliográficos
Autores principales: Tavares, William Corrêa, Seuánez, Héctor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433710/
https://www.ncbi.nlm.nih.gov/pubmed/28510580
http://dx.doi.org/10.1371/journal.pone.0177403