Cargando…

An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice

Dietary methionine restriction (MR) produces a coordinated series of transcriptional responses in peripheral tissues that limit fat accretion, remodel lipid metabolism in liver and adipose tissue, and improve overall insulin sensitivity. Hepatic sensing of reduced methionine leads to induction and r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghosh, Sujoy, Forney, Laura A., Wanders, Desiree, Stone, Kirsten P., Gettys, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433721/
https://www.ncbi.nlm.nih.gov/pubmed/28520765
http://dx.doi.org/10.1371/journal.pone.0177513