ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle contributes to disease progression; however the m...

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Detalles Bibliográficos
Autores principales: Gonzalez, David, Contreras, Osvaldo, Rebolledo, Daniela L., Espinoza, Juan Pablo, van Zundert, Brigitte, Brandan, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433732/
https://www.ncbi.nlm.nih.gov/pubmed/28520806
http://dx.doi.org/10.1371/journal.pone.0177649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433732/
https://www.ncbi.nlm.nih.gov/pubmed/28520806
http://dx.doi.org/10.1371/journal.pone.0177649

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