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Presynaptic Aβ40 prevents synapse addition in the adult Drosophila neuromuscular junction

Complexity in the processing of the Amyloid Precursor Protein, which generates a mixture of βamyloid peptides, lies beneath the difficulty in understanding the etiology of Alzheimer’s disease. Moreover, whether Aβ peptides have any physiological role in neurons is an unresolved question. By expressi...

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Detalles Bibliográficos
Autores principales: López-Arias, Begoña, Turiégano, Enrique, Monedero, Ignacio, Canal, Inmaculada, Torroja, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433741/
https://www.ncbi.nlm.nih.gov/pubmed/28520784
http://dx.doi.org/10.1371/journal.pone.0177541