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BIRC6 mediates imatinib resistance independently of Mcl-1

Baculoviral IAP repeat containing 6 (BIRC6) is a member of the inhibitors of apoptosis proteins (IAPs), a family of functionally and structurally related proteins that inhibit apoptosis. BIRC6 has been implicated in drug resistance in several different human cancers, however mechanisms regulating BI...

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Detalles Bibliográficos
Autores principales: Okumu, Denis O., East, Michael P., Levine, Merlin, Herring, Laura E., Zhang, Raymond, Gilbert, Thomas S. K., Litchfield, David W., Zhang, Yanping, Graves, Lee M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433768/
https://www.ncbi.nlm.nih.gov/pubmed/28520795
http://dx.doi.org/10.1371/journal.pone.0177871