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MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium

MyD88-mediated signaling downstream of Toll-like receptors and the IL-1 receptor family is critically involved in the induction of protective host responses upon infections. Although it is known that MyD88-deficient mice are highly susceptible to a wide range of bacterial infections, the cell type-s...

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Detalles Bibliográficos
Autores principales: Friedrich, Christin, Mamareli, Panagiota, Thiemann, Sophie, Kruse, Friederike, Wang, Zuobai, Holzmann, Bernhard, Strowig, Till, Sparwasser, Tim, Lochner, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433783/
https://www.ncbi.nlm.nih.gov/pubmed/28520792
http://dx.doi.org/10.1371/journal.ppat.1006357