Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing

Faithfull genome partitioning during cell division relies on the Spindle Assembly Checkpoint (SAC), a conserved signaling pathway that delays anaphase onset until all chromosomes are attached to spindle microtubules. Mps1 kinase is an upstream SAC regulator that promotes the assembly of an anaphase...

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Detalles Bibliográficos
Autores principales: Moura, Margarida, Osswald, Mariana, Leça, Nelson, Barbosa, João, Pereira, António J, Maiato, Helder, Sunkel, Claudio E, Conde, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433843/
https://www.ncbi.nlm.nih.gov/pubmed/28463114
http://dx.doi.org/10.7554/eLife.25366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433843/
https://www.ncbi.nlm.nih.gov/pubmed/28463114
http://dx.doi.org/10.7554/eLife.25366

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