Genetic Deletion of the Bacterial Sensor NOD2 Improves Murine Crohn’s Disease-like Ileitis Independent of Functional Dysbiosis

Although genetic polymorphisms in NOD2 (nucleotide-binding oligomerization domain-containing 2) have been associated with the pathogenesis of Crohn’s disease (CD), little is known regarding the role of wild-type (WT) NOD2 in the gut. To date, most murine studies addressing the role of WT Nod2 have b...

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Detalles Bibliográficos
Autores principales: Corridoni, D., Palacios, A. Rodriguez, Di Stefano, G., Di Martino, L., Antonopoulos, D.A., Chang, E.B., Arseneau, K.O., Pizarro, T.T., Cominelli, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433921/
https://www.ncbi.nlm.nih.gov/pubmed/27848951
http://dx.doi.org/10.1038/mi.2016.98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433921/
https://www.ncbi.nlm.nih.gov/pubmed/27848951
http://dx.doi.org/10.1038/mi.2016.98

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