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FGF23/FGFR4-mediated left ventricular hypertrophy is reversible

Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. Serum FGF23 levels are highly elevated in patients with chro...

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Detalles Bibliográficos
Autores principales: Grabner, Alexander, Schramm, Karla, Silswal, Neerupma, Hendrix, Matt, Yanucil, Christopher, Czaya, Brian, Singh, Saurav, Wolf, Myles, Hermann, Sven, Stypmann, Jörg, Di Marco, Giovana Seno, Brand, Marcus, Wacker, Michael J., Faul, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434018/
https://www.ncbi.nlm.nih.gov/pubmed/28512310
http://dx.doi.org/10.1038/s41598-017-02068-6