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A genetic screen in combination with biochemical analysis in Saccharomyces cerevisiae indicates that phenazine-1-carboxylic acid is harmful to vesicular trafficking and autophagy

The environmentally friendly antibiotic phenazine-1-carboxylic acid (PCA) protects plants, mammals and humans effectively against various fungal pathogens. However, the mechanism by which PCA inhibits or kills fungal pathogens is not fully understood. We analyzed the effects of PCA on the growth of...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolong, Zeng, Yan, Zhao, Xiu, Zou, Shenshen, He, Ya-Wen, Liang, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434042/
https://www.ncbi.nlm.nih.gov/pubmed/28512289
http://dx.doi.org/10.1038/s41598-017-01452-6