Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract

The selection of any specific immunization route is critical when defining future vaccine strategies against a genital infection like Chlamydia trachomatis (C.t.). An optimal Chlamydia vaccine needs to elicit mucosal immunity comprising both neutralizing IgA/IgG antibodies and strong Th1/Th17 respon...

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Detalles Bibliográficos
Autores principales: Wern, Jeanette Erbo, Sorensen, Maria Rathmann, Olsen, Anja Weinreich, Andersen, Peter, Follmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434101/
https://www.ncbi.nlm.nih.gov/pubmed/28567043
http://dx.doi.org/10.3389/fimmu.2017.00569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434101/
https://www.ncbi.nlm.nih.gov/pubmed/28567043
http://dx.doi.org/10.3389/fimmu.2017.00569

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