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Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract

The selection of any specific immunization route is critical when defining future vaccine strategies against a genital infection like Chlamydia trachomatis (C.t.). An optimal Chlamydia vaccine needs to elicit mucosal immunity comprising both neutralizing IgA/IgG antibodies and strong Th1/Th17 respon...

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Detalles Bibliográficos
Autores principales:	Wern, Jeanette Erbo, Sorensen, Maria Rathmann, Olsen, Anja Weinreich, Andersen, Peter, Follmann, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434101/ https://www.ncbi.nlm.nih.gov/pubmed/28567043 http://dx.doi.org/10.3389/fimmu.2017.00569

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