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Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway

Recent studies indicate that mitochondrial pathways of apoptosis are potential chemotherapeutic target for the treatment of esophageal cancer. Azoxystrobin (AZOX), a methoxyacrylate derived from the naturally occurring strobilurins, is a known fungicide acting as a ubiquinol oxidation (Qo) inhibitor...

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Detalles Bibliográficos
Autores principales: Shi, Xiao-ke, Bian, Xiao-bo, Huang, Tao, Wen, Bo, Zhao, Ling, Mu, Huai-xue, Fatima, Sarwat, Fan, Bao-min, Bian, Zhao-xiang, Huang, Lin-fang, Lin, Cheng-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434151/
https://www.ncbi.nlm.nih.gov/pubmed/28567017
http://dx.doi.org/10.3389/fphar.2017.00277