Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous disease in which glial cells participate in both disease onset and progression. Exosomal transfer of mutant copper-zinc superoxide...

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Detalles Bibliográficos
Autores principales: Pinto, Sara, Cunha, Carolina, Barbosa, Marta, Vaz, Ana R., Brites, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434170/
https://www.ncbi.nlm.nih.gov/pubmed/28567000
http://dx.doi.org/10.3389/fnins.2017.00273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434170/
https://www.ncbi.nlm.nih.gov/pubmed/28567000
http://dx.doi.org/10.3389/fnins.2017.00273

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