Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease

AIM: To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo. METHODS: The thiopurines azathioprine and 6-mercaptopurine have been a mainstay of inflammatory bowel disease (IBD) therapy for decades, but their mechanism of action in vivo remains...

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Detalles Bibliográficos
Autores principales: Lord, James D, Shows, Donna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434429/
https://www.ncbi.nlm.nih.gov/pubmed/28566883
http://dx.doi.org/10.3748/wjg.v23.i18.3240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434429/
https://www.ncbi.nlm.nih.gov/pubmed/28566883
http://dx.doi.org/10.3748/wjg.v23.i18.3240

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