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Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease
AIM: To identify which blood and mucosal lymphocyte populations are specifically depleted by thiopurine use in vivo. METHODS: The thiopurines azathioprine and 6-mercaptopurine have been a mainstay of inflammatory bowel disease (IBD) therapy for decades, but their mechanism of action in vivo remains...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Baishideng Publishing Group Inc
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434429/ https://www.ncbi.nlm.nih.gov/pubmed/28566883 http://dx.doi.org/10.3748/wjg.v23.i18.3240 |