Effect of oligonucleotide primers in determining viral variability within hosts

BACKGROUND: Genetic variability in viral populations is usually estimated by means of polymerase chain reaction (PCR) based methods in which the relative abundance of each amplicon is assumed to be proportional to the frequency of the corresponding template in the initial sample. Although bias in te...

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Detalles Bibliográficos
Autores principales: Bracho, Maria Alma, García-Robles, Inmaculada, Jiménez, Nuria, Torres-Puente, Manuela, Moya, Andrés, González-Candelas, Fernando
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC543450/
https://www.ncbi.nlm.nih.gov/pubmed/15588294
http://dx.doi.org/10.1186/1743-422X-1-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC543450/
https://www.ncbi.nlm.nih.gov/pubmed/15588294
http://dx.doi.org/10.1186/1743-422X-1-13

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