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Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1/Jagged1 pathway

BACKGROUND: Basic fibroblast growth factor (bFGF) plays an important role in promoting wound healing and reducing scar, but the possible molecular mechanisms are still unclear. Our previous studies have found that activating the Notch1/Jagged1 pathway can inhibit the differentiation of epidermal ste...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Shu, Bin, Xu, Yingbin, Zhu, Jiayuan, Liu, Jian, Zhou, Ziheng, Chen, Lei, Zhao, Jingling, Liu, Xusheng, Qi, Shaohai, Xiong, Kun, Xie, Julin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434520/
https://www.ncbi.nlm.nih.gov/pubmed/28511663
http://dx.doi.org/10.1186/s13287-017-0549-7