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ING3 promotes prostate cancer growth by activating the androgen receptor

BACKGROUND: The androgen receptor (AR) is a major driver of prostate cancer, and increased AR levels and co-activators of the receptor promote the development of prostate cancer. INhibitor of Growth (ING) proteins target lysine acetyltransferase or lysine deacetylase complexes to the histone H3K4Me3...

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Detalles Bibliográficos
Autores principales: Nabbi, Arash, McClurg, Urszula L., Thalappilly, Subhash, Almami, Amal, Mobahat, Mahsa, Bismar, Tarek A., Binda, Olivier, Riabowol, Karl T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434536/
https://www.ncbi.nlm.nih.gov/pubmed/28511652
http://dx.doi.org/10.1186/s12916-017-0854-0