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Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma
BACKGROUND: The prognosis of synovial sarcoma (SS), an aggressive soft tissue sarcoma, remains poor. We previously reported that c-MET or platelet-derived growth factor receptor α (PDGFRα) signalling pathway is related to SS progression based upon the findings of phospho-receptor tyrosine kinase (RT...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434537/ https://www.ncbi.nlm.nih.gov/pubmed/28511645 http://dx.doi.org/10.1186/s12885-017-3324-3 |