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A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions
BACKGROUND: Mechanical and biophysical properties of the cellular microenvironment regulate cell fate decisions. Mesenchymal stem cell (MSC) fate is influenced by past mechanical dosing (memory), but the mechanisms underlying this process have not yet been well defined. We have yet to understand how...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434622/ https://www.ncbi.nlm.nih.gov/pubmed/28511648 http://dx.doi.org/10.1186/s12918-017-0429-x |