Cargando…
A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions
BACKGROUND: Mechanical and biophysical properties of the cellular microenvironment regulate cell fate decisions. Mesenchymal stem cell (MSC) fate is influenced by past mechanical dosing (memory), but the mechanisms underlying this process have not yet been well defined. We have yet to understand how...
Autores principales: | Peng, Tao, Liu, Linan, MacLean, Adam L, Wong, Chi Wut, Zhao, Weian, Nie, Qing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434622/ https://www.ncbi.nlm.nih.gov/pubmed/28511648 http://dx.doi.org/10.1186/s12918-017-0429-x |
Ejemplares similares
-
The LINC complex, mechanotransduction, and mesenchymal stem cell function and fate
por: Bouzid, Tasneem, et al.
Publicado: (2019) -
Mechanotransduction: Tuning Stem Cells Fate
por: D'Angelo, Francesco, et al.
Publicado: (2011) -
Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model
por: MacLean, Adam L., et al.
Publicado: (2014) -
Memory and Modularity in Cell-Fate Decision Making
por: Norman, Thomas M., et al.
Publicado: (2013) -
The circadian clock has roles in mesenchymal stem cell fate decision
por: Gao, Wenzhen, et al.
Publicado: (2022)