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Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation

Aging is the most important risk factor for neurodegenerative diseases associated with pathological protein aggregation such as Alzheimer’s disease. Although aging is an important player, it remains unknown which molecular changes are relevant for disease initiation. Recently, it has become apparent...

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Detalles Bibliográficos
Autores principales: Groh, Nicole, Bühler, Anika, Huang, Chaolie, Li, Ka Wan, van Nierop, Pim, Smit, August B., Fändrich, Marcus, Baumann, Frank, David, Della C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434662/
https://www.ncbi.nlm.nih.gov/pubmed/28567012
http://dx.doi.org/10.3389/fnagi.2017.00138