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Specific targeting of the deubiquitinase and E3 ligase families with engineered ubiquitin variants
The ubiquitin proteasome system (UPS) has garnered much attention due to its potential for the development of therapeutics. Following a successful clinical application of general proteasome inhibitors much effort has been devoted to targeting individual UPS components including E3 enzymes and deubiq...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434665/ https://www.ncbi.nlm.nih.gov/pubmed/28580429 http://dx.doi.org/10.1002/btm2.10044 |