Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags

Small ubiquitin like modifier (SUMO) proteins are known to regulate many important cellular processes such as transcription and apoptosis. Recently, hybrid SUMO-ubiquitin chains containing SUMO-2 linked to Lys63-di-ubiquitin were found to play a major role in DNA repair. Despite some progress in und...

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Detalles Bibliográficos
Autores principales: Bondalapati, Somasekhar, Eid, Emad, Mali, Sachitanand M., Wolberger, Cynthia, Brik, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434752/
https://www.ncbi.nlm.nih.gov/pubmed/28580118
http://dx.doi.org/10.1039/c7sc00488e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434752/
https://www.ncbi.nlm.nih.gov/pubmed/28580118
http://dx.doi.org/10.1039/c7sc00488e

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