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Pretreatment with the ALDH2 agonist Alda-1 reduces intestinal injury induced by ischaemia and reperfusion in mice

Many studies demonstrate that activation of aldehyde dehydrogenase 2 (ALDH2) protects against oxidative stress via detoxification of cytotoxic aldehydes, and could attenuate cardiac, cerebral, lung and renal ischaemia–reperfusion (I/R) injuries. However, the effect of ALDH2 in intestinal I/R is unkn...

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Detalles Bibliográficos
Autores principales: Zhu, Qiankun, He, Guizhen, Wang, Jie, Wang, Yukang, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434792/
https://www.ncbi.nlm.nih.gov/pubmed/28325855
http://dx.doi.org/10.1042/CS20170074