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Card9 controls Dectin‐1‐induced T‐cell cytotoxicity and tumor growth in mice

Activation of the C‐type lectin receptor Dectin‐1 by β‐glucans triggers multiple signals within DCs that result in activation of innate immunity. While these mechanisms can potently prime CD8(+) cytotoxic T‐cell (CTL) responses without additional adjuvants, the Dectin‐1 effector pathways that contro...

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Detalles Bibliográficos
Autores principales: Haas, Tobias, Heidegger, Simon, Wintges, Alexander, Bscheider, Michael, Bek, Sarah, Fischer, Julius C., Eisenkolb, Gabriel, Schmickl, Martina, Spoerl, Silvia, Peschel, Christian, Poeck, Hendrik, Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434796/
https://www.ncbi.nlm.nih.gov/pubmed/28295265
http://dx.doi.org/10.1002/eji.201646775