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Card9 controls Dectin‐1‐induced T‐cell cytotoxicity and tumor growth in mice
Activation of the C‐type lectin receptor Dectin‐1 by β‐glucans triggers multiple signals within DCs that result in activation of innate immunity. While these mechanisms can potently prime CD8(+) cytotoxic T‐cell (CTL) responses without additional adjuvants, the Dectin‐1 effector pathways that contro...
Autores principales: | Haas, Tobias, Heidegger, Simon, Wintges, Alexander, Bscheider, Michael, Bek, Sarah, Fischer, Julius C., Eisenkolb, Gabriel, Schmickl, Martina, Spoerl, Silvia, Peschel, Christian, Poeck, Hendrik, Ruland, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434796/ https://www.ncbi.nlm.nih.gov/pubmed/28295265 http://dx.doi.org/10.1002/eji.201646775 |
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