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Misspecification of at‐risk periods and distributional assumptions in estimating COPD exacerbation rates: The resultant bias in treatment effect estimation
In trials comparing the rate of chronic obstructive pulmonary disease exacerbation between treatment arms, the rate is typically calculated on the basis of the whole of each patient's follow‐up period. However, the true time a patient is at risk should exclude periods in which an exacerbation e...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434805/ https://www.ncbi.nlm.nih.gov/pubmed/27966248 http://dx.doi.org/10.1002/pst.1798 |