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The StcE metalloprotease of enterohaemorrhagic Escherichia coli reduces the inner mucus layer and promotes adherence to human colonic epithelium ex vivo

Enterohaemorrhagic Escherichia coli (EHEC) is a major foodborne pathogen and tightly adheres to human colonic epithelium by forming attaching/effacing lesions. To reach the epithelial surface, EHEC must penetrate the thick mucus layer protecting the colonic epithelium. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Hews, Claire L., Tran, Seav‐Ly, Wegmann, Udo, Brett, Bernard, Walsham, Alistair D.S., Kavanaugh, Devon, Ward, Nicole J., Juge, Nathalie, Schüller, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434857/
https://www.ncbi.nlm.nih.gov/pubmed/28054754
http://dx.doi.org/10.1111/cmi.12717