Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM

The natural small molecule compound: 2,3,5,6-tetramethylpyrazine (TMP), is a major component of the Chinese medicine Chuanxiong, which has wide clinical applications in dilating blood vessels, inhibiting platelet aggregation and treating thrombosis. Recent work suggests that TMP is also an antitumou...

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Detalles Bibliográficos
Autores principales: Lan, Linhua, Guo, Miaomiao, Ai, Yong, Chen, Fuhong, Zhang, Ya, Xia, Lei, Huang, Dawei, Niu, Lili, Zheng, Ying, Suzuki, Carolyn K., Zhang, Yihua, Liu, Yongzhang, Lu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434891/
https://www.ncbi.nlm.nih.gov/pubmed/28465355
http://dx.doi.org/10.1042/BSR20170319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434891/
https://www.ncbi.nlm.nih.gov/pubmed/28465355
http://dx.doi.org/10.1042/BSR20170319

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