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The free energy of locking a ring: Changing a deoxyribonucleoside to a locked nucleic acid

Locked nucleic acid (LNA), a modified nucleoside which contains a bridging group across the ribose ring, improves the stability of DNA/RNA duplexes significantly, and therefore is of interest in biotechnology and gene therapy applications. In this study, we investigate the free energy change between...

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Detalles Bibliográficos
Autores principales:	Xu, You, Villa, Alessandra, Nilsson, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434909/ https://www.ncbi.nlm.nih.gov/pubmed/28101966 http://dx.doi.org/10.1002/jcc.24692

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