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Laser ablation electrospray ionization high‐resolution mass spectrometry for regulatory screening of domoic acid in shellfish

RATIONALE: Domoic acid (DA) is a potent neurotoxin that accumulates in shellfish. Routine testing involves homogenization, extraction and chromatographic analysis, with a run time of up to 30 min. Improving throughput using ambient ionization for direct analysis of DA in tissue would result in signi...

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Detalles Bibliográficos
Autores principales: Beach, Daniel G., Walsh, Callee M., Cantrell, Pamela, Rourke, Wade, O'Brien, Sinead, Reeves, Kelley, McCarron, Pearse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434922/
https://www.ncbi.nlm.nih.gov/pubmed/27534707
http://dx.doi.org/10.1002/rcm.7725