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Cocaine self-administration disrupted by the N-methyl-D-aspartate receptor antagonist ketamine: a randomized, crossover trial

Repeated drug consumption may progress to problematic use by triggering neuroplastic adaptations that attenuate sensitivity to natural rewards while increasing reactivity to craving and drug cues. Using an established laboratory model aimed at evaluating behavioral shifts in the salience of cocaine...

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Detalles Bibliográficos
Autores principales: Dakwar, E, Hart, CL, Levin, FR, Nunes, EV, Foltin, RW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435123/
https://www.ncbi.nlm.nih.gov/pubmed/27090301
http://dx.doi.org/10.1038/mp.2016.39