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Altered detrusor contractility in MPTP-treated common marmosets with bladder hyperreflexia

Bladder hyperreflexia is a common non-motor feature of Parkinson’s disease. We now report on the contractility of the isolated primate detrusor strips devoid of nerve input and show that following MPTP, the amplitude and frequency of spontaneous contraction was increased. These responses were unaffe...

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Detalles Bibliográficos
Autores principales: Pritchard, Sara, Jackson, Michael J., Hikima, Atsuko, Lione, Lisa, Benham, Christopher D., Chaudhuri, K. Ray, Rose, Sarah, Jenner, Peter, Iravani, Mahmoud M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435136/
https://www.ncbi.nlm.nih.gov/pubmed/28520722
http://dx.doi.org/10.1371/journal.pone.0175797