Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAH(enu2) mouse model of PKU

Phenylketonuria (PKU) is a genetic disease characterized by the inability to convert dietary phenylalanine to tyrosine by phenylalanine hydroxylase. Given the importance of gut microbes in digestion, a genetically engineered microbe could potentially degrade some ingested phenylalanine from the diet...

Descripción completa

Detalles Bibliográficos
Autores principales: Durrer, Katherine E., Allen, Michael S., Hunt von Herbing, Ione
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435137/
https://www.ncbi.nlm.nih.gov/pubmed/28520731
http://dx.doi.org/10.1371/journal.pone.0176286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435137/
https://www.ncbi.nlm.nih.gov/pubmed/28520731
http://dx.doi.org/10.1371/journal.pone.0176286

Ejemplares similares