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Comparative lytic efficacy of rt-PA and ultrasound in porcine versus human clots

INTRODUCTION: Porcine thrombi are employed routinely in preclinical models of ischemic stroke. In this study, we examined the differential lytic susceptibility of porcine and human whole blood clots with and without the use of microbubbles and ultrasound (US) as an adjuvant. MATERIALS AND METHODS: A...

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Detalles Bibliográficos
Autores principales: Huang, Shenwen, Shekhar, Himanshu, Holland, Christy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435301/
https://www.ncbi.nlm.nih.gov/pubmed/28545055
http://dx.doi.org/10.1371/journal.pone.0177786