Cargando…

Transcriptional activation of HIF-1 by a ROS-ERK axis underlies the resistance to photodynamic therapy

Photodynamic therapy (PDT), a promising treatment option for cancer, involves the activation of a photosensitizer (PS) by local irradiation with visible light. Excitation of the PS leads to a series of photochemical reactions and consequently the local generation of harmful reactive oxygen species (...

Descripción completa

Detalles Bibliográficos
Autores principales: Lamberti, María Julia, Pansa, María Florencia, Vera, Renzo Emanuel, Fernández-Zapico, Martín Ernesto, Rumie Vittar, Natalia Belén, Rivarola, Viviana Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435305/
https://www.ncbi.nlm.nih.gov/pubmed/28545088
http://dx.doi.org/10.1371/journal.pone.0177801