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Transcriptional activation of HIF-1 by a ROS-ERK axis underlies the resistance to photodynamic therapy
Photodynamic therapy (PDT), a promising treatment option for cancer, involves the activation of a photosensitizer (PS) by local irradiation with visible light. Excitation of the PS leads to a series of photochemical reactions and consequently the local generation of harmful reactive oxygen species (...
Autores principales: | Lamberti, María Julia, Pansa, María Florencia, Vera, Renzo Emanuel, Fernández-Zapico, Martín Ernesto, Rumie Vittar, Natalia Belén, Rivarola, Viviana Alicia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435305/ https://www.ncbi.nlm.nih.gov/pubmed/28545088 http://dx.doi.org/10.1371/journal.pone.0177801 |
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