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Autocrine expression of the epidermal growth factor receptor ligand heparin-binding EGF-like growth factor in cervical cancer

In cervical cancer, the epidermal growth factor receptor (EGFR) is overexpressed in 70–90% of the cases and has been associated with poor prognosis. EGFR-based therapy is currently being explored in cervical cancer. We investigated which EGFR ligand is primarily expressed in cervical cancer and whic...

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Detalles Bibliográficos
Autores principales: Schrevel, Marlies, Osse, E. Michelle, Prins, Frans A., Trimbos, J. Baptist M.Z., Fleuren, Gert Jan, Gorter, Arko, Jordanova, Ekaterina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435322/
https://www.ncbi.nlm.nih.gov/pubmed/28498437
http://dx.doi.org/10.3892/ijo.2017.3980