Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling

Prion diseases are neurodegenerative conditions caused by misfolding of the prion protein, leading to conspicuous neuronal loss and intense microgliosis. Recent experimental evidence point towards a protective role of microglia against prion-induced neurodegeneration, possibly through elimination of...

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Detalles Bibliográficos
Autores principales: Nuvolone, Mario, Paolucci, Marta, Sorce, Silvia, Kana, Veronika, Moos, Rita, Matozaki, Takashi, Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435345/
https://www.ncbi.nlm.nih.gov/pubmed/28545141
http://dx.doi.org/10.1371/journal.pone.0177876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435345/
https://www.ncbi.nlm.nih.gov/pubmed/28545141
http://dx.doi.org/10.1371/journal.pone.0177876

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