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Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling
Prion diseases are neurodegenerative conditions caused by misfolding of the prion protein, leading to conspicuous neuronal loss and intense microgliosis. Recent experimental evidence point towards a protective role of microglia against prion-induced neurodegeneration, possibly through elimination of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435345/ https://www.ncbi.nlm.nih.gov/pubmed/28545141 http://dx.doi.org/10.1371/journal.pone.0177876 |